Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL28396812 | 0.91 | EGLN1 (0.71) | EGLN1 | |
| Glycine SCHEMBL28394023 | 0.89 | EGLN1 (0.72) | EGLN1 | |
| Glycine SCHEMBL28398415 | 0.89 | EGLN1 (0.72) | EGLN1 | |
| Glycine SCHEMBL28396815 | 0.87 | EGLN1 (0.71) | EGLN1 | |
| Glycine SCHEMBL28392761 | 0.87 | EGLN1 (0.73) | EGLN1 | |
| Glycine SCHEMBL28398669 | 0.87 | EGLN1 (0.73) | EGLN1 | |
| Glycine SCHEMBL28406045 | 0.86 | EGLN1 (0.73) | EGLN1 | |
| Glycine SCHEMBL28401958 | 0.84 | EGLN1 (0.73) | EGLN1 | |
| Glycine SCHEMBL28392606 | 0.83 | EGLN1 (0.71) | EGLN1 | |
| Glycine SCHEMBL28393884 | 0.81 | EGLN1 (0.73) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759564-B | Triazole pyridine formyl glycine compound, method and medical application thereof | 中国药科大学 | 2020-05-22 | — | — | CN | disclosed |