SCHEMBL28400487

SCHEMBL28400487

CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](O)CN1C=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14415282 0.79
SCHEMBL4041777 0.77 ATM (0.34) DUT
SCHEMBL4041770 0.77 ATM (0.34) DUT
SCHEMBL20973729 0.77 ATM (0.34) DUT
SCHEMBL5569321 0.77 ATM (0.34) DUT
SCHEMBL28650340 0.76
SCHEMBL28650343 0.76
SCHEMBL16317135 0.74
SCHEMBL13598441 0.74 CYP1A2 (0.40)
SCHEMBL4274093 0.74 CYP1A2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108093640-B Site-specific antibody-drug conjugates ADC治疗股份有限公司 2022-05-17 CN disclosed
CN-105636613-B Pyrrolobenzodiazepines and conjugates thereof 麦迪穆有限责任公司 2020-02-07 CN disclosed