Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.69 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.69 |
| ▸ | WNT3A | P56704 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27702405 | 0.93 | DDB1 (0.61) | DDB1CRBNWNT3ANAMPTJAK2 | |
| SCHEMBL22324899 | 0.88 | DDB1 (0.67) | DDB1CRBNWNT3ANAMPTJAK2 | |
| SCHEMBL25093627 | 0.84 | DDB1 (0.58) | DDB1CRBNWNT3ANAMPTGPR119 | |
| SCHEMBL29497122 | 0.83 | DDB1 (0.60) | DDB1CRBNWNT3ANAMPTGPR119 | |
| SCHEMBL611718 | 0.83 | DDB1 (0.60) | DDB1CRBNWNT3ANAMPTGPR119 | |
| SCHEMBL666124 | 0.83 | DDB1 (0.60) | DDB1CRBNWNT3ANAMPTGPR119 | |
| SCHEMBL31737074 | 0.83 | DDB1 (0.60) | DDB1CRBNWNT3ANAMPTGPR119 | |
| SCHEMBL25931442 | 0.83 | DDB1 (0.60) | DDB1CRBNWNT3ANAMPTGPR119 | |
| SCHEMBL22895872 | 0.83 | DDB1 (0.63) | DDB1CRBNWNT3ANAMPTJAK1 | |
| SCHEMBL28550157 | 0.83 | DDB1 (0.63) | DDB1CRBNWNT3ANAMPTJAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759563-B | Preparation method of 4- (6-substituted aminopyridine-3-yl) piperidine-1-tert-butyl formate | 上海再启生物技术有限公司 | 2020-06-02 | — | — | CN | claimed |
| CN-107759563-B | Preparation method of 4- (6-substituted aminopyridine-3-yl) piperidine-1-tert-butyl formate | 上海再启生物技术有限公司 | 2020-06-02 | — | — | CN | disclosed |