Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 11/20 | 0.37 |
| ▸ | GCG | P01275 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 2/20 | 0.31 |
| ▸ | GIPR | P48546 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20907564 | 1.00 | GCGR (0.37) | GCGRGCGHDAC3NCOR1HDAC1 | |
| SCHEMBL21112825 | 0.84 | GCGR (0.38) | GCGRGCGHDAC3NCOR1HDAC1 | |
| SCHEMBL21112823 | 0.84 | GCGR (0.38) | GCGRGCGHDAC3NCOR1HDAC1 | |
| SCHEMBL20907613 | 0.81 | SMN1; SMN2 (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21149466 | 0.80 | MEN1 (0.35) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL20907804 | 0.80 | MEN1 (0.35) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL21149580 | 0.79 | NPC1 (0.36) | MEN1KMT2AALDH1A1HPGDMAOA | |
| SCHEMBL21148969 | 0.78 | RXFP1 (0.37) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL28401742 | 0.78 | RXFP1 (0.37) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL20907878 | 0.76 | PTPN1 (0.41) | MEN1KMT2AALDH1A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-B | 1-Benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-111212832-A | 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2020-05-29 | — | — | CN | disclosed |