Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212408 | 0.94 | ANO1 (0.34) | ABL1ANO1MAPK1RPS6KA1GSK3B | |
| SCHEMBL211561 | 0.92 | ABL1 (0.32) | ABL1ANO1MAPK1RPS6KA1GSK3B | |
| SCHEMBL211562 | 0.92 | ABL1 (0.32) | ABL1ANO1MAPK1RPS6KA1GSK3B | |
| SCHEMBL211560 | 0.92 | ABL1 (0.32) | ABL1ANO1MAPK1RPS6KA1GSK3B | |
| SCHEMBL2725708 | 0.92 | ABL1 (0.32) | ABL1ANO1MAPK1RPS6KA1 | |
| SCHEMBL212492 | 0.91 | ABL1 (0.32) | ABL1ANO1MAPK1RPS6KA1P2RX7 | |
| SCHEMBL2722512 | 0.91 | ABL1 (0.36) | ABL1ANO1 | |
| SCHEMBL4341224 | 0.91 | ABL1 (0.34) | ABL1ANO1MAPK1RPS6KA1P2RX7 | |
| SCHEMBL211782 | 0.90 | ABL1 (0.32) | ABL1ANO1MAPK1RPS6KA1 | |
| SCHEMBL211783 | 0.90 | ABL1 (0.32) | ABL1ANO1MAPK1RPS6KA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195328-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Incorporated (US) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009023193-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |