Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 17/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888846 | 0.86 | EP300 (1.00) | EP300HDAC1HDAC6 | |
| SCHEMBL6045652 | 0.84 | EP300 (0.72) | EP300ADCY5 | |
| SCHEMBL6045566 | 0.84 | EP300 (0.72) | EP300ADCY5 | |
| SCHEMBL28397440 | 0.84 | HDAC1 (0.73) | EP300HDAC1HDAC6ADCY5 | |
| SCHEMBL6045654 | 0.80 | EP300 (0.66) | EP300ADCY5 | |
| SCHEMBL6045687 | 0.78 | EP300 (0.62) | EP300ADCY5 | |
| SCHEMBL28407185 | 0.77 | EP300 (1.00) | EP300 | |
| SCHEMBL13599654 | 0.76 | EP300 (0.63) | EP300HDAC1HDAC6ADCY5 | |
| SCHEMBL28397710 | 0.76 | EP300 (1.00) | EP300 | |
| SCHEMBL28401109 | 0.75 | EP300 (1.00) | EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106883217-B | Nucleoside base hydroxamic acid derivative compound and preparation method and application thereof | 清华大学深圳研究生院 | 2020-05-22 | — | — | CN | disclosed |