Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 5/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | GPER1 | Q99527 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28403736 | 1.00 | MKNK1 (0.35) | MKNK1MKNK2BRD4CREBBPEP300 | |
| SCHEMBL21150320 | 0.88 | MKNK1 (0.34) | MKNK1MKNK2BRD4CREBBPEP300 | |
| SCHEMBL21150362 | 0.88 | JAK1 (0.36) | MKNK1MKNK2BRD4CREBBPEP300 | |
| SCHEMBL20907580 | 0.88 | JAK1 (0.36) | MKNK1MKNK2BRD4CREBBPEP300 | |
| SCHEMBL20908223 | 0.87 | MKNK1 (0.32) | MKNK1MKNK2BRD4CREBBPEP300 | |
| SCHEMBL29640359 | 0.87 | MKNK1 (0.32) | MKNK1MKNK2BRD4CREBBPEP300 | |
| SCHEMBL21112969 | 0.87 | CREBBP (0.36) | MKNK1MKNK2BRD4CREBBPEP300 | |
| SCHEMBL21112970 | 0.87 | CREBBP (0.36) | MKNK1MKNK2BRD4CREBBPEP300 | |
| SCHEMBL30557222 | 0.87 | BRD4 (0.35) | MKNK1MKNK2BRD4CREBBPEP300 | |
| SCHEMBL21112675 | 0.74 | EP300 (0.33) | MKNK1MKNK2BRD4CREBBPEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-B | 1-Benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-111212832-A | 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2020-05-29 | — | — | CN | disclosed |