Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.61 |
| ▸ | ITK | Q08881 | 9/20 | 0.61 |
| ▸ | BTK | Q06187 | 7/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | BLK | P51451 | 1/20 | 0.60 |
| ▸ | TEK | Q02763 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 2/20 | 0.52 |
| ▸ | JAK3 | P52333 | 2/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | TEC | P42680 | 1/20 | 0.52 |
| ▸ | TXK | P42681 | 1/20 | 0.52 |
| ▸ | BMX | P51813 | 1/20 | 0.52 |
| ▸ | CD69 | Q07108 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397441 | 0.88 | BTK (0.60) | EGFRITKBTKSRCBLK | |
| SCHEMBL28398256 | 0.88 | PIK3CD (0.66) | EGFRITKBTKSRCBLK | |
| SCHEMBL28397630 | 0.87 | BTK (0.61) | EGFRITKBTKSRCBLK | |
| SCHEMBL28402552 | 0.85 | EGFR (0.68) | EGFRITKBTKSRCBLK | |
| SCHEMBL28762043 | 0.79 | PIK3CD (0.79) | EGFRBTKSRCBLKJAK3 | |
| SCHEMBL29717490 | 0.79 | PIK3CD (0.79) | EGFRBTKSRCBLKJAK3 | |
| SCHEMBL6483156 | 0.78 | EGFR (0.64) | EGFRITKBTKSRCBLK | |
| SCHEMBL30423295 | 0.78 | EGFR (0.75) | EGFRITKBTKSRCBLK | |
| SCHEMBL28400978 | 0.78 | EGFR (0.75) | EGFRITKBTKSRCBLK | |
| SCHEMBL30423172 | 0.77 | EGFR (0.61) | EGFRITKBTKSRCBLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057021-B | S-triazine compound, preparation method and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | claimed |
| CN-111057021-A | S-triazine compound and its preparing method and use | 中国药科大学 | 2020-04-24 | — | — | CN | claimed |
| CN-111057021-B | S-triazine compound, preparation method and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-111057021-A | S-triazine compound and its preparing method and use | 中国药科大学 | 2020-04-24 | — | — | CN | disclosed |