Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.63 |
| ▸ | STAT1 | P42224 | 1/20 | 0.63 |
| ▸ | TOP1 | P11387 | 3/20 | 0.38 |
| ▸ | CYCS | P99999 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462569 | 0.97 | STAT3 (0.59) | STAT3STAT1TOP1CYCSESR1 | |
| SCHEMBL31276120 | 0.95 | STAT3 (0.55) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL28311233 | 0.95 | STAT3 (0.55) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL28188073 | 0.93 | STAT3 (0.72) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL28008850 | 0.90 | STAT3 (0.67) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL27940870 | 0.89 | STAT3 (0.63) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL29253192 | 0.89 | STAT3 (0.63) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL28939046 | 0.88 | STAT3 (0.62) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL27571718 | 0.88 | STAT3 (0.65) | STAT3STAT1TOP1CYCSMAPK13 | |
| SCHEMBL29904993 | 0.88 | STAT3 (0.62) | STAT3STAT1TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233876-B | Fluorescent probe for detecting hydrogen sulfide and preparation method and application thereof | 湖南科技大学 | 2021-11-09 | — | — | CN | claimed |
| CN-111233876-A | Fluorescent probe for rapidly detecting hydrogen sulfide and preparation method and application thereof | 湖南科技大学 | 2020-06-05 | — | — | CN | claimed |
| CN-111233876-B | Fluorescent probe for detecting hydrogen sulfide and preparation method and application thereof | 湖南科技大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-111233876-A | Fluorescent probe for rapidly detecting hydrogen sulfide and preparation method and application thereof | 湖南科技大学 | 2020-06-05 | — | — | CN | disclosed |