Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 16/20 | 0.52 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28406844 | 0.93 | IDO1 (0.61) | IDO1ALDH1A1 | |
| SCHEMBL28406867 | 0.92 | IDO1 (0.49) | IDO1ALDH1A1TSHR | |
| SCHEMBL28401052 | 0.92 | IDO1 (0.52) | IDO1F10F2 | |
| SCHEMBL28397873 | 0.91 | IDO1 (0.48) | IDO1F10ALDH1A1 | |
| SCHEMBL28401138 | 0.89 | IDO1 (0.49) | IDO1 | |
| SCHEMBL28398505 | 0.89 | IDO1 (0.54) | IDO1 | |
| SCHEMBL28399112 | 0.89 | IDO1 (0.46) | IDO1 | |
| SCHEMBL28403303 | 0.86 | IDO1 (0.56) | IDO1 | |
| SCHEMBL23663508 | 0.85 | IDO1 (0.54) | IDO1 | |
| SCHEMBL28406914 | 0.85 | IDO1 (0.60) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153850-B | Indole compound, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2021-08-13 | — | — | CN | claimed |
| CN-111153850-A | Indole compound, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2020-05-15 | — | — | CN | claimed |
| CN-111153850-B | Indole compound, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2021-08-13 | — | — | CN | disclosed |
| CN-111153850-A | Indole compound, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2020-05-15 | — | — | CN | disclosed |