Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17265688 | 0.84 | MAPK1 (0.48) | MEN1KMT2AMAPK1CYP1A2NPSR1 | |
| SCHEMBL17265687 | 0.84 | MAPK1 (0.48) | MEN1KMT2AMAPK1CYP1A2NPSR1 | |
| SCHEMBL31184810 | 0.83 | MAPK1 (0.54) | MEN1KMT2AMAPK1CYP1A2NPSR1 | |
| SCHEMBL21563188 | 0.81 | MEN1 (0.49) | MEN1KMT2AMAPK1CYP1A2NPSR1 | |
| SCHEMBL21550966 | 0.81 | MEN1 (0.49) | MEN1KMT2AMAPK1CYP1A2NPSR1 | |
| SCHEMBL21550965 | 0.81 | MEN1 (0.49) | MEN1KMT2AMAPK1CYP1A2NPSR1 | |
| SCHEMBL30099261 | 0.81 | MEN1 (0.49) | MEN1KMT2AMAPK1CYP1A2NPSR1 | |
| SCHEMBL29851229 | 0.81 | MEN1 (0.49) | MEN1KMT2AMAPK1CYP1A2NPSR1 | |
| SCHEMBL16277503 | 0.81 | KMT2A (0.57) | MEN1KMT2AMAPK1CYP1A2NPSR1 | |
| SCHEMBL16277504 | 0.81 | KMT2A (0.57) | MEN1KMT2AMAPK1CYP1A2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111039845-A | Preparation method of 4-fluoro-7-bromoisatin | 大连奇凯医药科技有限公司 | 2020-04-21 | — | — | CN | claimed |
| CN-111039845-A | Preparation method of 4-fluoro-7-bromoisatin | 大连奇凯医药科技有限公司 | 2020-04-21 | — | — | CN | disclosed |