Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20758902 | 0.81 | GRM4 (0.72) | GRM4 | |
| SCHEMBL20761675 | 0.81 | GRM4 (0.72) | GRM4 | |
| SCHEMBL20741023 | 0.79 | GRM4 (0.77) | GRM4 | |
| SCHEMBL20741022 | 0.79 | GRM4 (0.77) | GRM4 | |
| SCHEMBL20741015 | 0.77 | GRM4 (0.61) | GRM4 | |
| SCHEMBL20741016 | 0.77 | GRM4 (0.61) | GRM4 | |
| SCHEMBL20741057 | 0.77 | GRM4 (0.63) | GRM4 | |
| SCHEMBL20741060 | 0.77 | GRM4 (0.63) | GRM4 | |
| SCHEMBL20759120 | 0.75 | GRM4 (1.00) | GRM4 | |
| SCHEMBL20758744 | 0.75 | GRM4 (1.00) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225913-A | Indazole compounds as allosteric enhancers of MGLUR4, compositions, and methods of treating neurological dysfunction | 范德比尔特大学 | 2020-06-02 | — | — | CN | disclosed |