Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 7/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22247486 | 0.93 | KDM1A (0.35) | KDM1ACHRNA3CHRNB2CHRNB4CHRNA7 | |
| SCHEMBL23012629 | 0.85 | HRH3 (0.41) | CHRNA3CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL7943211 | 0.78 | KDM1A (0.42) | KDM1AEP300ACACB | |
| SCHEMBL31508227 | 0.77 | FEN1 (0.44) | KDM1AEP300ACACB | |
| SCHEMBL18097298 | 0.75 | BACE1 (0.38) | ACACB | |
| SCHEMBL18097301 | 0.75 | BACE1 (0.38) | ACACB | |
| SCHEMBL4445675 | 0.74 | FFAR4 (0.39) | KDM1AEP300 | |
| SCHEMBL20469409 | 0.73 | EP300 (0.42) | KDM1AEP300ACACB | |
| SCHEMBL16838835 | 0.73 | ACACB (0.37) | KDM1AEP300ACACB | |
| SCHEMBL12248343 | 0.73 | ACACB (0.39) | KDM1AEP300ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132961-A | Bisaryloxy derivatives as TTX-S blockers | 拉夸里亚创药株式会社 | 2020-05-08 | — | — | CN | disclosed |