SCHEMBL28408692

SCHEMBL28408692

CCCCOc1nccc(CCC)n1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 3/20 0.43
CYP2D6 P10635 10/20 0.40
CYP3A4 P08684 6/20 0.40
KCNH2 Q12809 1/20 0.39
CYP19A1 P11511 8/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C9 P11712 7/20 0.36
CYP2C19 P33261 7/20 0.36
CYP1A2 P05177 6/20 0.36
TLR8 Q9NR97 1/20 0.36
SREBF2 Q12772 1/20 0.35
LTA4H P09960 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27993620 0.79 KCNH2 (0.43) CYP2D6KCNH2LMNACYP1A2TLR8
SCHEMBL14234022 0.78 KCNH2 (0.41) CYP3A4KCNH2KDM4ELMNATSHR
SCHEMBL18081852 0.78 MAPK8 (0.45) MAPK8CYP2D6CYP3A4CYP19A1LMNA
SCHEMBL4266406 0.78 MAPK8 (0.45) MAPK8CYP2D6CYP3A4CYP19A1LMNA
SCHEMBL27579341 0.77 KCNH2 (0.50) KCNH2TLR8
SCHEMBL16631783 0.76 MAPK8 (0.44) MAPK8CYP2D6CYP3A4CYP19A1CYP2C9
SCHEMBL16631778 0.76 MCHR1 (0.47) MAPK8CYP2D6CYP3A4CYP19A1KDM4E
SCHEMBL16815642 0.75 MAPK8 (0.44) MAPK8LMNACYP1A2LTA4H
SCHEMBL27592765 0.75 KDM4E (0.42) CYP3A4KCNH2KDM4ELMNATSHR
SCHEMBL17029323 0.74 MAPK8 (0.42) MAPK8CYP2D6CYP3A4CYP19A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111246738-A Tank mix 巴斯夫欧洲公司 2020-06-05 CN disclosed