Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | CNR1 | P21554 | 2/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | GOT1 | P17174 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28882017 | 0.91 | CNR1 (0.78) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL29883691 | 0.91 | CNR1 (0.78) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL8177075 | 0.85 | EGFR (0.65) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL4606056 | 0.85 | EPHX1 (0.81) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL2827311 | 0.84 | KMT2A (0.72) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL22588919 | 0.84 | KMT2A (0.72) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL4897395 | 0.84 | CNR1 (0.74) | KMT2ANPC1RAB9AMAPTCNR1 | |
| SCHEMBL28411219 | 0.83 | CNR1 (0.69) | KMT2AMEN1NPC1RAB9ACNR1 | |
| SCHEMBL10192070 | 0.83 | KMT2A (0.82) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL14466285 | 0.83 | KMT2A (0.71) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111100038-A | Urea compound with gibberellin function inhibition activity and preparation method and application thereof | 中国农业大学 | 2020-05-05 | — | — | CN | disclosed |