Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 5/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28427882 | 0.93 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28417442 | 0.91 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28417692 | 0.90 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28417694 | 0.90 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28410605 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28410607 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28415599 | 0.86 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28418812 | 0.86 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28418816 | 0.86 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28415601 | 0.86 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320578-A | Propenone derivative for removing N-methylfleroxacin and preparation method and application thereof | 郑州工业应用技术学院 | 2020-06-23 | — | — | CN | disclosed |