SCHEMBL28411802

SCHEMBL28411802

Nn1cc(I)c2cncnc21

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19710954 0.77 CYP17A1 (0.31)
SCHEMBL13616224 0.77 BRD4 (0.42)
SCHEMBL12984352 0.74 NTRK1 (0.41)
SCHEMBL14655900 0.69 DDB1 (0.30) DDB1CRBN
SCHEMBL12985356 0.68 NTRK1 (0.40)
SCHEMBL4008391 0.68 CSNK2A2 (0.38)
SCHEMBL12985080 0.67 NTRK1 (0.42)
SCHEMBL12984981 0.67 NTRK1 (0.42)
SCHEMBL12934038 0.65 DYRK3 (0.50)
SCHEMBL12985020 0.65 NTRK1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111100130-B 4-amino pyrrolopyrimidine derivatives, and preparation method and application thereof 四川大学 2022-07-15 CN disclosed
CN-111100130-A 4-amino pyrrolopyrimidine derivatives, and preparation method and application thereof 四川大学 2020-05-05 CN disclosed