SCHEMBL28412652

SCHEMBL28412652

CCCCCCCCCCCCn1c2ccccc2c2cc(C=O)ccc21

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.66
CNR2 P34972 12/20 0.58
PSEN1 P49768 7/20 0.56
PSEN2 P49810 7/20 0.56
APH1B Q8WW43 7/20 0.56
NCSTN Q92542 7/20 0.56
APH1A Q96BI3 7/20 0.56
PSENEN Q9NZ42 7/20 0.56
CNR1 P21554 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28142613 1.00 PTGER4 (0.66) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL28217298 1.00 PTGER4 (0.66) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL28369278 1.00 PTGER4 (0.66) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL8701533 1.00 PTGER4 (0.66) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL28446594 1.00 PTGER4 (0.66) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL4821945 1.00 PTGER4 (0.66) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL5153575 1.00 PTGER4 (0.66) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL31174405 1.00 PTGER4 (0.66) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL600436 0.99 PTGER4 (0.67) PTGER4CNR2PSEN1PSEN2APH1B
SCHEMBL9019646 0.94 PTGER4 (0.69) PTGER4CNR2PSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110128413-B 5-acetyl-4- (N-substituted carbazolyl) -6-methyl-3, 4-dihydropyrimidine-2-ketone and preparation method thereof 陕西科技大学 2022-03-25 CN disclosed
CN-111100114-B Fluorescent probe capable of rapidly displaying normal state and near-zero state of cell membrane potential and application thereof 山东大学 2022-03-22 CN disclosed
CN-111072632-B Fluorescent probe for displaying two states of cell membrane potential by using fluorescent image and application thereof 山东大学 2022-03-22 CN disclosed
CN-109053548-B Schiff base containing carbazolyl and preparation method thereof 陕西科技大学 2021-12-21 CN disclosed
CN-111100114-A Fluorescent probe capable of rapidly displaying normal state and near-zero state of cell membrane potential and application thereof 山东大学 2020-05-05 CN disclosed
CN-111072632-A Fluorescent probe for displaying two states of cell membrane potential by using fluorescent image and application thereof 山东大学 2020-04-28 CN disclosed