Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.62 |
| ▸ | PPARD | Q03181 | 12/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974927 | 0.80 | KDR (0.43) | PPARAPPARDKCNH2PPARGKDR | |
| SCHEMBL13359231 | 0.79 | PPARA (0.78) | PPARAPPARDKCNH2PPARG | |
| SCHEMBL4465972 | 0.79 | PPARA (0.63) | PPARAPPARDKCNH2PPARG | |
| SCHEMBL11893217 | 0.79 | PPARA (0.63) | PPARAPPARDKCNH2PPARG | |
| SCHEMBL22278935 | 0.78 | PPARA (0.64) | PPARAPPARDKCNH2PPARG | |
| SCHEMBL25947232 | 0.78 | PPARA (0.62) | PPARAPPARDKCNH2PPARG | |
| SCHEMBL21219011 | 0.78 | CYP1A2 (0.56) | KDRDAO | |
| SCHEMBL499507 | 0.78 | CYP1A2 (0.56) | KDRDAO | |
| SCHEMBL4468143 | 0.78 | PPARA (0.65) | PPARAPPARDKCNH2PPARG | |
| SCHEMBL11893126 | 0.78 | PPARA (0.65) | PPARAPPARDKCNH2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111183132-A | Preparation method of Elafibranor and novel synthetic intermediate | 阿德万泰克咨询与技术股份有限公司 | 2020-05-19 | — | — | CN | disclosed |