Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 3/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665020 | 0.98 | PARP15 (0.55) | PARP15PARP10PARP2TDP1KDM1A | |
| SCHEMBL8930160 | 0.98 | PARP15 (0.55) | PARP15PARP10PARP2TDP1KDM1A | |
| SCHEMBL14451132 | 0.90 | HPGD (0.52) | PARP15PARP10PARP2TDP1KDM1A | |
| SCHEMBL11164865 | 0.90 | PARP15 (0.57) | PARP15PARP10PARP2TDP1KDM1A | |
| SCHEMBL18374444 | 0.90 | PARP15 (0.57) | PARP15PARP10PARP2TDP1KDM1A | |
| SCHEMBL17296955 | 0.89 | PARP15 (0.47) | PARP15PARP10PARP2TDP1KDM1A | |
| SCHEMBL16141973 | 0.89 | PARP15 (0.51) | PARP15PARP10PARP2TDP1KDM1A | |
| SCHEMBL81903 | 0.88 | PARP15 (0.58) | PARP15PARP10PARP2TDP1KDM1A | |
| SCHEMBL29024848 | 0.87 | PARP15 (0.64) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL17296954 | 0.86 | TP53 (0.57) | PARP15PARP10PARP2TDP1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466803-A | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-111132976-B | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-111132976-A | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2020-05-08 | — | — | CN | disclosed |