SCHEMBL28413632

SCHEMBL28413632

NC(=O)OC1CCC(c2ccccc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.47
AKR1C1 Q04828 1/20 0.47
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
KDM4E B2RXH2 3/20 0.44
FABP7 O15540 1/20 0.42
FABP5 Q01469 1/20 0.42
SLC18A3 Q16572 6/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41
ADAM10 O14672 1/20 0.41
MMP2 P08253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24040028 1.00 AKR1C3 (0.47) AKR1C3AKR1C1NPC1RAB9AKDM4E
SCHEMBL24040040 1.00 AKR1C3 (0.47) AKR1C3AKR1C1NPC1RAB9AKDM4E
SCHEMBL21826495 0.85 AKR1C3 (0.50) AKR1C3AKR1C1NPC1RAB9AKDM4E
SCHEMBL21826434 0.85 AKR1C3 (0.50) AKR1C3AKR1C1NPC1RAB9AKDM4E
SCHEMBL21826494 0.85 AKR1C3 (0.50) AKR1C3AKR1C1NPC1RAB9AKDM4E
SCHEMBL21826435 0.85 AKR1C3 (0.50) AKR1C3AKR1C1NPC1RAB9AKDM4E
SCHEMBL28669857 0.84 AKR1C3 (0.44) AKR1C3AKR1C1KDM4EFABP7FABP5
Carbamic Acid SCHEMBL9679981 0.82 AKR1C3 (0.59) AKR1C3AKR1C1NPC1RAB9AKDM4E
SCHEMBL10892937 0.82 AKR1C3 (0.51) AKR1C3AKR1C1NPC1RAB9AKDM4E
SCHEMBL8384792 0.82 SLC18A3 (0.55) AKR1C3AKR1C1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667215-B Broad-spectrum antiviral medicine for resisting coronavirus 堪萨斯州立大学研究基金会 2026-05-19 CN disclosed
CN-111247119-B Amidine and guanidine derivatives, preparation method and application thereof in medicines 四川科伦博泰生物医药股份有限公司 2023-02-03 CN disclosed
CN-115667215-A Broad-spectrum antiviral medicine for resisting coronavirus 堪萨斯州立大学研究基金会 2023-01-31 CN disclosed
CN-111247119-A Amidine and guanidine derivatives, preparation method and application thereof in medicines 四川科伦博泰生物医药股份有限公司 2020-06-05 CN disclosed