Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 18/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350635 | 0.86 | SLC22A12 (0.54) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL21331853 | 0.85 | CCNC (0.46) | SLC22A12CCNCCDK8 | |
| SCHEMBL21331873 | 0.83 | SLC22A12 (0.50) | SLC22A12CCNCCDK8 | |
| SCHEMBL17540560 | 0.83 | SLC22A12 (0.69) | SLC22A12SLC22A6SLC22A11CCNCCDK8 | |
| SCHEMBL21333890 | 0.83 | CCNC (0.44) | SLC22A12CCNCCDK8 | |
| SCHEMBL21350908 | 0.83 | CCNC (0.44) | SLC22A12CCNCCDK8 | |
| SCHEMBL21331867 | 0.83 | CCNC (0.44) | SLC22A12CCNCCDK8 | |
| SCHEMBL21350520 | 0.80 | CCNC (0.52) | CCNCCDK8 | |
| SCHEMBL21331865 | 0.80 | SLC22A12 (0.52) | SLC22A12SLC22A6SLC22A11CYP19A1ABCG2 | |
| SCHEMBL21331852 | 0.80 | CYP2C9 (0.54) | SLC22A12CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440397-B | 3- (naphthalene-1-methyl substituted) pyridine derivative and synthesis method and application thereof | 南方医科大学 | 2020-06-05 | — | — | CN | disclosed |