Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.59 |
| ▸ | RARA | P10276 | 5/20 | 0.45 |
| ▸ | RARB | P10826 | 5/20 | 0.45 |
| ▸ | RARG | P13631 | 5/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839980 | 0.92 | S1PR1 (0.59) | S1PR1RARARARBRARGS1PR3 | |
| SCHEMBL2774286 | 0.86 | S1PR1 (0.57) | S1PR1RARARARBRARGS1PR3 | |
| SCHEMBL2805606 | 0.84 | S1PR1 (0.60) | S1PR1RARARARBRARGS1PR3 | |
| SCHEMBL2804370 | 0.81 | S1PR1 (0.55) | S1PR1RARARARBRARGS1PR3 | |
| SCHEMBL2774458 | 0.79 | S1PR1 (0.58) | S1PR1RARARARBRARGS1PR3 | |
| SCHEMBL2771897 | 0.78 | S1PR1 (0.62) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2775573 | 0.76 | S1PR1 (0.60) | S1PR1RARARARBRARGS1PR3 | |
| SCHEMBL2809248 | 0.76 | S1PR1 (0.66) | S1PR1RARARARBRARGS1PR3 | |
| SCHEMBL3766503 | 0.74 | S1PR1 (1.00) | S1PR1 | |
| SCHEMBL2774407 | 0.74 | S1PR1 (0.73) | S1PR1RARARARBRARGS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193125-A2 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009043889-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2009-04-09 | — | — | WO | disclosed |