Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | USP2 | O75604 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.49 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.49 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.49 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALPG | P10696 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28417347 | 1.00 | CHAT (0.56) | CHATMEN1KMT2ARAB9AUSP2 | |
| SCHEMBL29441870 | 0.85 | KDM4E (0.64) | MEN1KMT2AATMALDH1A1KDM4E | |
| SCHEMBL14982726 | 0.85 | KDM4E (0.64) | MEN1KMT2AATMALDH1A1KDM4E | |
| SCHEMBL13988760 | 0.85 | KDM4E (0.64) | MEN1KMT2AATMALDH1A1KDM4E | |
| SCHEMBL31084773 | 0.85 | KDM4E (0.64) | MEN1KMT2AATMALDH1A1KDM4E | |
| SCHEMBL13142004 | 0.85 | KDM4E (0.64) | MEN1KMT2AATMALDH1A1KDM4E | |
| SCHEMBL16756631 | 0.85 | KDM4E (0.64) | MEN1KMT2AATMALDH1A1KDM4E | |
| SCHEMBL15624213 | 0.83 | CHAT (0.49) | CHATMEN1KMT2ARAB9AUSP2 | |
| Iodide SCHEMBL29038331 | 0.82 | KDM4E (0.52) | ATMAPOBEC3GKDM4EAPOBEC3AL3MBTL1 | |
| SCHEMBL17905913 | 0.82 | CHAT (0.54) | CHATMEN1KMT2ARAB9AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111304778-A | Method for preparing two-photon fluorescent skin-color spandex | 华峰重庆氨纶有限公司 | 2020-06-19 | — | — | CN | disclosed |