Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13597426 | 0.81 | IDO1 (0.58) | IDO1AGXTMAOBGLATAAR1 | |
| SCHEMBL31370399 | 0.81 | IDO1 (0.58) | IDO1AGXTMAOBGLATAAR1 | |
| SCHEMBL10835147 | 0.79 | IDO1 (0.43) | IDO1AGXTMAOBTAAR1CYP1A2 | |
| Boric Acid SCHEMBL28083926 | 0.78 | IDO1 (0.47) | IDO1AGXTMAOBGLATAAR1 | |
| SCHEMBL21824246 | 0.74 | IDO1 (0.58) | IDO1AGXTMAOBGLATAAR1 | |
| SCHEMBL27219447 | 0.71 | IDO1 (0.55) | IDO1AGXTMAOBGLATAAR1 | |
| SCHEMBL29830809 | 0.71 | IDO1 (0.64) | IDO1AGXTMAOBTAAR1MAOA | |
| SCHEMBL514760 | 0.71 | IDO1 (0.64) | IDO1AGXTMAOBTAAR1MAOA | |
| SCHEMBL2717710 | 0.71 | IDO1 (0.50) | IDO1AGXTMAOBGLACYP1A2 | |
| SCHEMBL1767187 | 0.70 | IDO1 (0.69) | IDO1AGXTMAOBTAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285850-B | Isoindoline compounds, preparation method thereof, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-04-22 | — | — | CN | disclosed |
| CN-111285850-A | Isoindoline compounds, preparation method thereof, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2020-06-16 | — | — | CN | disclosed |