Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | APLNR | P35414 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | GLP1R | P43220 | 1/20 | 0.57 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547876 | 0.92 | GNRHR (0.78) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL20547877 | 0.92 | GNRHR (0.78) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL28421982 | 0.90 | GNRHR (0.67) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL28419485 | 0.88 | GNRHR (0.79) | GNRHRCYP3A4 | |
| SCHEMBL28419487 | 0.88 | GNRHR (0.79) | GNRHRCYP3A4 | |
| SCHEMBL28418291 | 0.87 | GNRHR (0.62) | GNRHRCYP3A4 | |
| SCHEMBL28418260 | 0.86 | GNRHR (0.54) | GNRHRCYP3A4 | |
| SCHEMBL28421910 | 0.85 | GNRHR (0.61) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL28421914 | 0.84 | GNRHR (0.59) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL28421940 | 0.84 | GNRHR (0.59) | GNRHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333587-B | Substituted pyrimidine-2, 4 (1H, 3H) -dione derivatives and uses thereof | 东莞市东阳光新药研发有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-111333587-A | Substituted pyrimidine-2, 4(1H,3H) -dione derivatives and uses thereof | 东莞市东阳光新药研发有限公司 | 2020-06-26 | — | — | CN | disclosed |