Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30102615 | 1.00 | STING1 (0.85) | STING1 | |
| SCHEMBL19451685 | 1.00 | STING1 (0.85) | STING1 | |
| SCHEMBL19451705 | 0.98 | STING1 (0.82) | STING1 | |
| SCHEMBL20066382 | 0.97 | STING1 (0.83) | STING1 | |
| SCHEMBL25074046 | 0.96 | STING1 (0.80) | STING1 | |
| SCHEMBL29012748 | 0.96 | STING1 (0.80) | STING1 | |
| SCHEMBL20889108 | 0.96 | STING1 (0.80) | STING1 | |
| SCHEMBL22151435 | 0.96 | STING1 (0.82) | STING1 | |
| SCHEMBL25076770 | 0.96 | STING1 (0.79) | STING1 | |
| SCHEMBL19451494 | 0.95 | STING1 (0.95) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608443-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-111194214-A | Methods of administering STING agonists | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-05-22 | — | — | CN | claimed |
| CN-118215475-A | Adjuvant compositions comprising STING agonists | 葛兰素史克生物有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113549110-A | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-109608443-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-109071514-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-111417630-A | Modulators of interferon gene stimulating factor (STING) | 葛兰素史克知识产权开发有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-111194214-A | Methods of administering STING agonists | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-05-22 | — | — | CN | disclosed |