SCHEMBL28420145

SCHEMBL28420145

[Li]C1C=Cc2c(Br)cccc21

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.31
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28424119 0.77 KDM1A (0.31) KDM1AMEN1GAAKMT2A
SCHEMBL29118170 0.75 KDM1A (0.31) KDM1AMEN1GAAKMT2A
SCHEMBL29120979 0.75 KDM1A (0.32) KDM1AMEN1GAAKMT2A
SCHEMBL29118184 0.75 KDM1A (0.31) KDM1AMEN1GAAKMT2A
SCHEMBL1452567 0.75 KDM1A (0.32) KDM1AMEN1GAAKMT2A
SCHEMBL23360990 0.75 KDM1A (0.31) KDM1AMEN1GAAKMT2A
SCHEMBL28418578 0.75 KDM1A (0.31) KDM1AMEN1GAAKMT2A
SCHEMBL1452294 0.73 KDM1A (0.31) KDM1A
SCHEMBL2971137 0.72 KDM1A (0.30) KDM1A
SCHEMBL1452682 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111372954-B Preparation of polyethylene (bis) silicon-bridged metallocenes with broad molecular weight distribution and molecular weight 埃克森美孚化学专利公司 2022-06-28 CN disclosed
CN-111372954-A Preparation of polyethylene (bis) silicon-bridged metallocenes with broad molecular weight distribution and molecular weight 埃克森美孚化学专利公司 2020-07-03 CN disclosed