SCHEMBL28420569

SCHEMBL28420569

CC(C)=S.NCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.75
HRH3 Q9Y5N1 1/20 0.58
LOXL2 Q9Y4K0 1/20 0.52
CYP2A6 P11509 1/20 0.48
BACE1 P56817 2/20 0.47
IDO1 P14902 2/20 0.45
AGXT P21549 2/20 0.45
ABCC4 O15439 1/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 1/20 0.45
PTGS1 P23219 1/20 0.45
HTT P42858 1/20 0.45
HDAC1 Q13547 1/20 0.44
ADRB2 P07550 1/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
BACE2 Q9Y5Z0 1/20 0.43
CSNK2A1 P68400 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL4936110 0.88 TAAR1 (0.75) TAAR1HRH3LOXL2CYP2A6BACE1
SCHEMBL22291708 0.87 TAAR1 (1.00) TAAR1HRH3LOXL2CYP2A6IDO1
SCHEMBL22202237 0.87 TAAR1 (1.00) TAAR1HRH3LOXL2CYP2A6IDO1
SCHEMBL28208288 0.87 TAAR1 (1.00) TAAR1HRH3LOXL2CYP2A6IDO1
SCHEMBL131842 0.87 TAAR1 (1.00) TAAR1HRH3LOXL2CYP2A6IDO1
Hydrochloric Acid SCHEMBL1661202 0.84 TAAR1 (0.95) TAAR1HRH3LOXL2CYP2A6IDO1
Hydrochloric Acid SCHEMBL7921699 0.84 TAAR1 (0.95) TAAR1HRH3LOXL2CYP2A6IDO1
SCHEMBL28420570 0.83 TAAR1 (0.75) TAAR1HRH3LOXL2CYP2A6BACE1
Acetic Acid SCHEMBL28208961 0.82 TAAR1 (0.67) TAAR1HRH3LOXL2CYP2A6BACE1
SCHEMBL28164006 0.80 TAAR1 (0.86) TAAR1HRH3LOXL2CYP2A6IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111378162-A Energy absorption method based on dynamic polymer 翁秋梅 2020-07-07 CN disclosed