SCHEMBL28422210

SCHEMBL28422210

CCCC(C)c1ccccc1-c1ccccc1S

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.34
FFAR1 O14842 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
ALDH1A1 P00352 1/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14864537 0.86 TSHR (0.43) TSHRSMN1; SMN2FFAR1GPR84
SCHEMBL28416841 0.85 TSHR (0.53) TSHRALDH1A1
SCHEMBL982415 0.80 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1
SCHEMBL31380293 0.80 TSHR (0.48) TSHRSMN1; SMN2FFAR1GPR84
SCHEMBL15536289 0.79 KDM4E (0.40) TSHRSMN1; SMN2FFAR1GPR84ALDH1A1
SCHEMBL11443355 0.76 ESR2 (0.38) TSHRSMN1; SMN2ALDH1A1
SCHEMBL5588012 0.76 TSHR (0.49) TSHRALDH1A1
SCHEMBL15105377 0.75 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1
SCHEMBL10669560 0.74 TSHR (0.33) TSHRSMN1; SMN2
SCHEMBL9563375 0.74 ABL1 (0.42) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111205424-B Modified resin and resin composition 旭化成株式会社 2022-04-08 CN disclosed
CN-113929866-A Modified resin and resin composition 旭化成株式会社 2022-01-14 CN disclosed
CN-107629183-B Modified resin and resin composition 旭化成株式会社 2021-01-05 CN disclosed
CN-111205424-A Modified resin and resin composition 旭化成株式会社 2020-05-29 CN disclosed