SCHEMBL28422286

SCHEMBL28422286

CO[C@@]1(c2ccc(F)c(Cc3ccccc3)c2)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.46
SLC5A1 P13866 12/20 0.44
CHRM1 P11229 1/20 0.37
ADRA1A P35348 1/20 0.37
SLC6A3 Q01959 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28531779 0.83 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL18197572 0.83 SLC5A2 (0.59) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL3302392 0.83 SLC5A2 (0.59) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL12416634 0.83 SLC5A2 (0.49) SLC5A2SLC5A1
SCHEMBL8229734 0.81 SLC5A2 (0.39) SLC5A2SLC5A1
SCHEMBL2216297 0.81 SLC5A2 (0.39) SLC5A2SLC5A1
SCHEMBL17924 0.81 SLC5A2 (0.41) SLC5A2SLC5A1
SCHEMBL29354 0.81 SLC5A2 (0.41) SLC5A2SLC5A1
SCHEMBL17961 0.80 SLC5A2 (0.41) SLC5A2SLC5A1
SCHEMBL25568 0.80 SLC5A2 (0.40) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108218928-B Bicyclic derivatives of glucoside, preparation method and application thereof 华润双鹤药业股份有限公司 2020-06-30 CN disclosed