Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28589485 | 0.97 | KMT2A (0.59) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL28763237 | 0.94 | KMT2A (0.53) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL31396644 | 0.94 | KMT2A (0.53) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL28876550 | 0.87 | KMT2A (0.46) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL28964033 | 0.84 | KMT2A (0.49) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL28417308 | 0.83 | CYP11B1 (0.41) | KMT2AHTTSMN1; SMN2TDP1CHRNA3 | |
| SCHEMBL28944840 | 0.81 | KMT2A (0.58) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL9153828 | 0.80 | KMT2A (0.43) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL9153824 | 0.80 | KMT2A (0.43) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| Hydrochloric Acid SCHEMBL28944862 | 0.80 | KMT2A (0.57) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344287-B | Novel substituted biaryl compounds as indoleamine 2, 3-dioxygenase (IDO) inhibitors | 默沙东有限责任公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-111344287-A | Novel substituted biaryl compounds as indoleamine 2, 3-dioxygenase (IDO) inhibitors | 默沙东公司 | 2020-06-26 | — | — | CN | disclosed |