Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.67 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.53 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.51 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488791 | 0.83 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL18207342 | 0.83 | TLR7 (0.63) | TLR7TLR8TRAP1 | |
| SCHEMBL18207604 | 0.83 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL18207673 | 0.82 | TLR7 (0.67) | TLR7TLR8HSP90B1TRAP1 | |
| SCHEMBL29488793 | 0.82 | TLR7 (0.67) | TLR7TLR8HSP90B1TRAP1 | |
| SCHEMBL18207584 | 0.82 | TLR7 (0.65) | TLR7TLR8 | |
| SCHEMBL18207658 | 0.82 | TLR7 (0.74) | TLR7 | |
| SCHEMBL18207494 | 0.81 | TLR7 (0.64) | TLR7TLR8 | |
| SCHEMBL19924997 | 0.81 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL18207267 | 0.81 | TLR7 (1.00) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107580596-B | Sulfimidoylpurine ketone compounds and derivatives for the treatment and prevention of viral infections | 豪夫迈·罗氏有限公司 | 2020-07-14 | — | — | CN | disclosed |