Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.66 |
| ▸ | ESRRG | P62508 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5012511 | 0.98 | EPHX2 (0.64) | EPHX2NR1H4ESRRGHDAC1SRD5A2 | |
| SCHEMBL17806562 | 0.94 | EPHX2 (0.60) | EPHX2NR1H4ESRRGHDAC1SRD5A2 | |
| SCHEMBL4671943 | 0.88 | PARP10 (0.70) | EPHX2NR1H4ESRRGALDH1A1KMT2A | |
| SCHEMBL27989128 | 0.86 | EPHX2 (0.51) | EPHX2NR1H4ESRRGHDAC1SRD5A2 | |
| SCHEMBL28573695 | 0.85 | EPHX2 (0.60) | EPHX2NR1H4ESRRGHDAC1SRD5A2 | |
| SCHEMBL7302042 | 0.85 | HDAC3 (0.73) | EPHX2NR1H4MEN1KMT2ANPC1 | |
| SCHEMBL1019153 | 0.84 | EPHX2 (0.50) | EPHX2NR1H4ESRRGHDAC1SRD5A2 | |
| SCHEMBL17292714 | 0.84 | NR1H4 (0.51) | EPHX2NR1H4ESRRGHDAC1SRD5A2 | |
| SCHEMBL11583494 | 0.82 | HDAC1 (0.55) | EPHX2NR1H4ESRRGHDAC1SRD5A2 | |
| SCHEMBL2677683 | 0.82 | EPHX2 (0.49) | EPHX2NR1H4ESRRGHDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1063 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371298-A | Method for efficiently synthesizing indenone compound | 南阳师范学院 | 2025-01-28 | — | — | CN | claimed |
| WO-2025009910-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 부산대학교 산학협력단 | 2025-01-09 | — | — | WO | claimed |
| CN-118344283-A | Trifluoromethyl unit-containing substituted 2-piperidone compound and synthesis method thereof | 西南交通大学 | 2024-07-16 | — | — | CN | claimed |
| CN-115724780-A | Acyl thiourea compound based on hydrophobic label, preparation method thereof and application of acyl thiourea compound in resisting influenza A virus | 武汉大学 | 2023-03-03 | — | — | CN | claimed |
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | claimed |
| EP-3280419-A1 | INDAZOLE AND AZAINDAZOLE BTK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2018-02-14 | — | — | EP | claimed |
| EP-1656144-B2 | TRP-P8 ACTIVE COMPOUNDS AND THERAPEUTIC TREATMENT METHODS | GENENTECH INC (US) | 2017-12-20 | — | — | EP | claimed |
| WO-2016164285-A1 | INDAZOLE AND AZAINDAZOLE BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-10-13 | — | — | WO | claimed |
| US-20150274661-A1 | INDOL-AMIDE COMPOUNDS AS BETA-AMYLOID INHBITORS | HOFFMANN-LA ROCHE INC. (US) | 2015-10-01 | — | — | US | claimed |
| EP-2909190-A1 | INDOL-AMIDE COMPOUNDS AS BETA-AMYLOID INHBITORS | F. Hoffmann-La Roche AG (CH) | 2015-08-26 | — | — | EP | claimed |
| EP-1007037-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-06-14 | — | — | EP | claimed |
| EP-0999834-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-05-17 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | claimed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | claimed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | claimed |
| WO-1999000126-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | claimed |
| WO-1999000127-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | claimed |
| US-5409808-A | Excellent sensitivity and gradation; improved storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1995-04-25 | — | — | US | claimed |
| WO-1994005642-A1 | INDAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274661-A1 | INDOL-AMIDE COMPOUNDS AS BETA-AMYLOID INHBITORS | APP, BACE1, IAPP | EPHX2 2108/4885NR1H4 761/4885ESRRG 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.