Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA1 | Q13131 | 7/20 | 1.00 |
| ▸ | PRKAA2 | P54646 | 6/20 | 1.00 |
| ▸ | KDR | P35968 | 9/20 | 0.81 |
| ▸ | TLK2 | Q86UE8 | 3/20 | 0.81 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.80 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.80 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.79 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.79 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.79 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.79 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.79 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.79 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.79 |
| ▸ | PLK4 | O00444 | 2/20 | 0.77 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.77 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856752 | 1.00 | PRKAA1 (1.00) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL2116298 | 1.00 | PRKAA1 (1.00) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| Trifluoroacetic Acid SCHEMBL29281305 | 0.95 | PRKAA1 (0.90) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL2088460 | 0.94 | PRKAA1 (0.90) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL20805259 | 0.93 | PRKAA1 (0.86) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL28435599 | 0.91 | PRKAA1 (0.84) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL29856566 | 0.91 | KDR (0.86) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL14047978 | 0.91 | KDR (0.86) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL28435601 | 0.91 | PRKAA1 (0.84) | PRKAA1PRKAA2KDRTLK2PDGFRB | |
| SCHEMBL13960774 | 0.91 | PRKAA1 (0.83) | PRKAA1PRKAA2KDRTLK2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111298127-A | Composition comprising histamine release-promoting substance and inhibitory compound, and oral solid preparation containing the same | 黄泳华 | 2020-06-19 | — | — | CN | claimed |
| CN-111298127-A | Composition comprising histamine release-promoting substance and inhibitory compound, and oral solid preparation containing the same | 黄泳华 | 2020-06-19 | — | — | CN | disclosed |