Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | IL6 | P05231 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL28675793 | 0.89 | TLR7 (0.62) | TLR7 | |
| Propane SCHEMBL28477001 | 0.86 | TLR7 (0.65) | TLR7 | |
| Propane SCHEMBL28426047 | 0.86 | TLR7 (0.62) | TLR7 | |
| Propane SCHEMBL28417406 | 0.84 | TLR7 (0.59) | TLR7 | |
| SCHEMBL21318965 | 0.84 | TLR7 (0.67) | TLR7ADORA1 | |
| Propane SCHEMBL28424662 | 0.83 | TLR7 (0.63) | TLR7 | |
| Propane SCHEMBL28422651 | 0.83 | TLR7 (0.63) | TLR7 | |
| Propane SCHEMBL28428265 | 0.83 | TLR7 (0.64) | TLR7 | |
| SCHEMBL18207590 | 0.79 | TLR7 (0.64) | TLR7ADORA1IL6 | |
| SCHEMBL18207571 | 0.78 | TLR7 (0.65) | TLR7ADORA1IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107580596-B | Sulfimidoylpurine ketone compounds and derivatives for the treatment and prevention of viral infections | 豪夫迈·罗氏有限公司 | 2020-07-14 | — | — | CN | disclosed |