SCHEMBL28428170

SCHEMBL28428170

CCC[S+]([O-])c1nc(N)c2[nH]c(=O)n(Cc3cncnc3)c2n1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28426078 0.88 TLR7 (0.62) TLR7
SCHEMBL18207289 0.88 TLR7 (0.65) TLR7
SCHEMBL18207821 0.85 TLR7 (0.61) TLR7
SCHEMBL18207428 0.85 TLR7 (0.62) TLR7
SCHEMBL18207590 0.85 TLR7 (0.64) TLR7
SCHEMBL18207373 0.84 TLR7 (0.62) TLR7
SCHEMBL18207646 0.84 TLR7 (0.62) TLR7
SCHEMBL18207465 0.83 TLR7 (0.64) TLR7
SCHEMBL18207696 0.83 TLR7 (0.64) TLR7
SCHEMBL18207367 0.82 TLR7 (0.67) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107580596-B Sulfimidoylpurine ketone compounds and derivatives for the treatment and prevention of viral infections 豪夫迈·罗氏有限公司 2020-07-14 CN disclosed