Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 7/20 | 0.57 |
| ▸ | BRD4 | O60885 | 7/20 | 0.55 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22464808 | 0.94 | CRBN (0.59) | MAP1LC3BBRD4CRBN | |
| SCHEMBL29137874 | 0.94 | CRBN (0.59) | MAP1LC3BBRD4CRBN | |
| SCHEMBL23772949 | 0.94 | CRBN (0.59) | MAP1LC3BBRD4CRBN | |
| SCHEMBL20362334 | 0.94 | CRBN (0.59) | MAP1LC3BBRD4CRBN | |
| SCHEMBL22464461 | 0.93 | CRBN (0.60) | MAP1LC3BBRD4CRBN | |
| SCHEMBL464519 | 0.92 | CRBN (0.60) | MAP1LC3BBRD4CRBN | |
| SCHEMBL26321035 | 0.91 | CRBN (0.63) | MAP1LC3BBRD4CRBN | |
| SCHEMBL26317744 | 0.91 | CRBN (0.63) | MAP1LC3BBRD4CRBN | |
| SCHEMBL26323874 | 0.91 | CRBN (0.63) | MAP1LC3BBRD4CRBN | |
| SCHEMBL26323878 | 0.91 | CRBN (0.63) | MAP1LC3BBRD4CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214227-A | Heterocyclic compound and application thereof | 上海青玄生物科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-111285849-A | Compound for targeted degradation of ALK, c-Met and ROS1 proteins and preparation method thereof | 上海青东生物科技有限公司 | 2020-06-16 | — | — | CN | disclosed |