Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723123 | 0.90 | MAPT (0.67) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL20919340 | 0.90 | MAPT (0.67) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL28431136 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL20918249 | 0.85 | CA1 (0.51) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL31723141 | 0.85 | CA1 (0.51) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL20923496 | 0.83 | KMT2A (0.68) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL31723118 | 0.83 | KMT2A (0.68) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL31723158 | 0.79 | MAPT (0.68) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL28431175 | 0.79 | MAPT (0.68) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL31723127 | 0.78 | KMT2A (0.52) | KDM4EALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699174-B1 | COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME | ILAB (KR) | 2025-11-12 | — | — | EP | claimed |
| CN-111315730-A | Composition for preventing or treating tumor necrosis factor-related diseases comprising novel derivative as active ingredient and method for inhibiting tumor necrosis factor activity using the same | 艾伊莱布 | 2020-06-19 | — | — | CN | claimed |
| CN-111315730-A | Composition for preventing or treating tumor necrosis factor-related diseases comprising novel derivative as active ingredient and method for inhibiting tumor necrosis factor activity using the same | 艾伊莱布 | 2020-06-19 | — | — | CN | disclosed |