Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28429377 | 0.86 | APP (0.46) | APPAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28420997 | 0.85 | APP (0.46) | APPAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6079942 | 0.83 | APP (0.44) | APPAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28425581 | 0.83 | APP (0.41) | APPAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28425288 | 0.83 | APP (0.41) | APPAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28426659 | 0.82 | APP (0.43) | APPALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28423535 | 0.81 | APP (0.41) | APPSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL6079981 | 0.80 | APP (0.49) | APPAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6080028 | 0.80 | APP (0.41) | APPAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6080639 | 0.80 | APP (0.43) | APPAKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357880-B | Folded body-based chiral fluorescent compound with circular polarization luminescence property and preparation method and application thereof | 北京师范大学 | 2020-07-03 | — | — | CN | disclosed |