SCHEMBL28430686

SCHEMBL28430686

FCCc1ccc2c(c1)OCCO2

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.56
LMNA P02545 7/20 0.49
HTT P42858 3/20 0.49
ALDH1A1 P00352 3/20 0.49
THRB P10828 1/20 0.49
CYP2D6 P10635 1/20 0.47
NPC1 O15118 2/20 0.47
CALM1 P0DP23 1/20 0.45
RAB9A P51151 2/20 0.44
USP2 O75604 1/20 0.44
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1253622 0.84 TAAR1 (0.79) TAAR1LMNAHTTALDH1A1THRB
SCHEMBL27751635 0.83 CYP2D6 (0.50) TAAR1LMNAHTTALDH1A1THRB
Hydrochloric Acid SCHEMBL30459386 0.82 TAAR1 (0.76) TAAR1LMNAHTTALDH1A1THRB
Hydrochloric Acid SCHEMBL26657866 0.82 TAAR1 (0.76) TAAR1LMNAHTTALDH1A1THRB
SCHEMBL19904410 0.81 TAAR1 (0.62) TAAR1LMNAHTTALDH1A1THRB
SCHEMBL8255914 0.80 TAAR1 (0.52) TAAR1LMNAHTTALDH1A1THRB
SCHEMBL4081586 0.80 TAAR1 (0.52) TAAR1LMNAHTTALDH1A1THRB
SCHEMBL315045 0.80 TAAR1 (0.52) TAAR1LMNAHTTALDH1A1THRB
SCHEMBL3777135 0.80 TAAR1 (0.52) TAAR1LMNAHTTALDH1A1THRB
SCHEMBL5657606 0.80 TAAR1 (0.52) TAAR1LMNAHTTALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107628926-B Preparation method of monofluoroethyl substituted aromatic compound 四川理工学院 2020-07-28 CN disclosed