Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KLK7 | P49862 | 2/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28431032 | 1.00 | MAPT (0.55) | MAPTKLK7KLK5ANPEPPOLB | |
| SCHEMBL30266675 | 0.98 | MAPT (0.54) | MAPTKLK7KLK5ANPEPPOLB | |
| SCHEMBL28897027 | 0.98 | MAPT (0.54) | MAPTKLK7KLK5ANPEPPOLB | |
| SCHEMBL30266615 | 0.98 | MAPT (0.54) | MAPTKLK7KLK5ANPEPPOLB | |
| SCHEMBL28436040 | 0.98 | MAPT (0.54) | MAPTKLK7KLK5ANPEPPOLB | |
| SCHEMBL20530077 | 0.94 | MAPT (0.58) | MAPTKLK7KLK5ANPEPMEN1 | |
| SCHEMBL20530079 | 0.94 | MAPT (0.58) | MAPTKLK7KLK5ANPEPMEN1 | |
| SCHEMBL23447583 | 0.92 | MEN1 (0.53) | MAPTKLK7KLK5ANPEPPOLB | |
| SCHEMBL28896921 | 0.91 | MAPT (0.51) | MAPTKLK7KLK5POLBMAPK1 | |
| SCHEMBL30266826 | 0.91 | MAPT (0.51) | MAPTKLK7KLK5POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484543-B | Lipopeptide TLR2 agonist and medicinal composition and application thereof | 复旦大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-111484543-A | Lipopeptide T L R2 agonist and medicinal composition and application thereof | 复旦大学 | 2020-08-04 | — | — | CN | disclosed |