Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 19/20 | 0.81 |
| ▸ | STK17B | O94768 | 15/20 | 0.81 |
| ▸ | AURKA | O14965 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154731 | 0.90 | STK17A (1.00) | STK17ASTK17B | |
| SCHEMBL20154744 | 0.88 | STK17A (1.00) | STK17ASTK17B | |
| SCHEMBL22508275 | 0.88 | STK17A (0.81) | STK17ASTK17B | |
| SCHEMBL21364895 | 0.88 | STK17A (0.81) | STK17ASTK17B | |
| SCHEMBL20154805 | 0.88 | STK17A (1.00) | STK17ASTK17B | |
| SCHEMBL21364914 | 0.87 | STK17A (0.77) | STK17ASTK17B | |
| SCHEMBL20154743 | 0.86 | STK17A (1.00) | STK17ASTK17B | |
| SCHEMBL20154734 | 0.85 | STK17A (1.00) | STK17ASTK17B | |
| SCHEMBL20154804 | 0.85 | STK17A (1.00) | STK17ASTK17B | |
| SCHEMBL20154739 | 0.85 | STK17A (1.00) | STK17ASTK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114344-B | Novel pyrimidine compound, method for preparing same, and pharmaceutical composition containing same as active ingredient for preventing or treating cancer and inflammatory disease | 韩国化学研究院 | 2020-06-16 | — | — | CN | disclosed |