Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.43 |
| ▸ | IDO1 | P14902 | 6/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23647770 | 0.93 | IDO1 (0.47) | TRPV1IDO1EPHX2KDRGAA | |
| SCHEMBL28897469 | 0.92 | IDO1 (0.45) | IDO1MAPTKMT2ASMN1; SMN2RAF1 | |
| SCHEMBL28451242 | 0.90 | TRPV1 (0.45) | TRPV1IDO1EPHX2KDRGAA | |
| SCHEMBL28443050 | 0.89 | IDO1 (0.48) | IDO1MAPTKMT2A | |
| SCHEMBL28439109 | 0.87 | IDO1 (0.48) | IDO1EPHX2GAAMAPTXBP1 | |
| SCHEMBL23658938 | 0.86 | IDO1 (0.57) | IDO1KMT2ARAF1 | |
| SCHEMBL28435093 | 0.84 | IDO1 (0.50) | IDO1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL28437071 | 0.83 | IDO1 (0.48) | IDO1 | |
| SCHEMBL28897468 | 0.83 | TRPV1 (0.47) | TRPV1IDO1EPHX2KDRGAA | |
| SCHEMBL28437205 | 0.82 | TRPV1 (0.44) | TRPV1IDO1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153846-B | Pyrrole compound, preparation method thereof, pharmaceutical composition and application | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2021-08-31 | — | — | CN | disclosed |
| CN-111153846-A | Pyrrole compound, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2020-05-15 | — | — | CN | disclosed |