Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.50 |
| ▸ | RET | P07949 | 13/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | KIF5B | P33176 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589289 | 0.88 | EGLN1 (0.46) | EGLN1RETJAK2KIF5BKDR | |
| Hydrochloric Acid SCHEMBL29629385 | 0.87 | EGLN1 (0.45) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL28441796 | 0.86 | EGLN1 (0.44) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL21744559 | 0.83 | EGLN1 (0.45) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL21744564 | 0.83 | EGLN1 (0.45) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL21744566 | 0.83 | EGLN1 (0.45) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL22701706 | 0.83 | EGLN1 (0.50) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL23929930 | 0.82 | EGLN1 (0.46) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL23929932 | 0.82 | EGLN1 (0.46) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL19364255 | 0.81 | RET (0.49) | EGLN1RETJAK2KIF5BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478519-B | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111484479-B | Azacyclic compounds, pharmaceutical compositions containing the same, and methods of making and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-114478519-A | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2022083741-A1 | PYRAZOLOPYRIDINE COMPOUND OR SALT THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2022-04-28 | — | — | WO | disclosed |
| CN-111484479-A | Nitrogen heterocyclic compound, pharmaceutical composition containing nitrogen heterocyclic compound, preparation method and application of nitrogen heterocyclic compound | 四川科伦博泰生物医药股份有限公司 | 2020-08-04 | — | — | CN | disclosed |