Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 20/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29859912 | 1.00 | CXCR4 (0.73) | CXCR4CYP2D6CYP3A4CHRM2DRD2 | |
| SCHEMBL2507349 | 0.94 | CXCR4 (0.83) | CXCR4CYP2D6CYP3A4CHRM2DRD2 | |
| SCHEMBL29823655 | 0.94 | CXCR4 (0.83) | CXCR4CYP2D6CYP3A4CHRM2DRD2 | |
| Bromide SCHEMBL1897567 | 0.93 | CXCR4 (0.81) | CXCR4CYP2D6CYP3A4CHRM2DRD2 | |
| SCHEMBL28446985 | 0.91 | CXCR4 (0.88) | CXCR4CYP2D6CYP3A4CHRM2DRD2 | |
| SCHEMBL28445662 | 0.86 | CXCR4 (0.69) | CXCR4CYP2D6CYP3A4CHRM2DRD2 | |
| SCHEMBL4065830 | 0.85 | CXCR4 (0.85) | CXCR4CYP2D6CYP3A4CHRM2DRD2 | |
| SCHEMBL29823518 | 0.84 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2DRD2 | |
| SCHEMBL1878773 | 0.84 | CXCR4 (1.00) | CXCR4CYP2D6CYP3A4CHRM2DRD2 | |
| Bromide SCHEMBL5141033 | 0.84 | CXCR4 (0.84) | CXCR4CYP2D6CYP3A4CHRM2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902411-A | Compositions and methods for expanding hematopoietic stem and progenitor cells and treating inherited metabolic disorders | 美真达治疗公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111683669-A | Compositions and methods for hematopoietic stem and progenitor cell transplantation therapy | 美真达治疗公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-111542597-A | Compositions and methods for expanding hematopoietic stem and progenitor cells | 美真达治疗公司 | 2020-08-14 | — | — | CN | disclosed |