Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23350444 | 1.00 | KDM1A (0.44) | KDM1AMAOBBTKEPHX1CTSK | |
| SCHEMBL22961611 | 0.85 | KDM1A (0.46) | KDM1AMAOBBTKEPHX1CTSK | |
| SCHEMBL1422281 | 0.85 | KDM1A (0.46) | KDM1AMAOBBTKEPHX1CTSK | |
| SCHEMBL21207007 | 0.83 | BTK (0.51) | KDM1AMAOBBTKEPHX1CTSK | |
| SCHEMBL28429309 | 0.81 | KDM1A (0.43) | KDM1AMAOBBTKEPHX1CTSK | |
| SCHEMBL19021200 | 0.81 | KDM1A (0.43) | KDM1AMAOBBTKEPHX1CTSK | |
| SCHEMBL28429307 | 0.81 | KDM1A (0.43) | KDM1AMAOBBTKEPHX1CTSK | |
| SCHEMBL12812406 | 0.80 | KDM1A (0.49) | KDM1AMAOBBTKEPHX1CTSK | |
| SCHEMBL14335260 | 0.80 | KDM1A (0.49) | KDM1AMAOBBTKEPHX1CTSK | |
| SCHEMBL8228036 | 0.80 | KDM1A (0.49) | KDM1AMAOBBTKEPHX1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479814-A | Fused pyridines as H-PGDS inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-07-31 | — | — | CN | disclosed |