Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 5/20 | 0.54 |
| ▸ | FLT3 | P36888 | 5/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28896995 | 0.93 | JAK2 (0.57) | JAK2FLT3SLC6A3TAAR1 | |
| SCHEMBL28434573 | 0.91 | JAK2 (0.67) | JAK2FLT3 | |
| SCHEMBL28442728 | 0.91 | JAK2 (0.67) | JAK2FLT3SLC6A3TAAR1 | |
| SCHEMBL28447921 | 0.90 | JAK2 (0.53) | JAK2FLT3 | |
| SCHEMBL28451446 | 0.90 | JAK2 (0.53) | JAK2FLT3 | |
| SCHEMBL28440889 | 0.90 | JAK2 (0.68) | JAK2FLT3 | |
| SCHEMBL28439354 | 0.90 | JAK2 (0.57) | JAK2FLT3 | |
| SCHEMBL28442025 | 0.90 | JAK2 (0.51) | JAK2FLT3 | |
| SCHEMBL28451389 | 0.90 | JAK2 (0.57) | JAK2FLT3SLC6A3TAAR1 | |
| SCHEMBL28443300 | 0.90 | JAK2 (0.57) | JAK2FLT3SLC6A3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423384-B | 2-aminopyrimidine compounds and application thereof | 沈阳药科大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-111423384-A | 2-aminopyrimidine compounds and application thereof | 沈阳药科大学 | 2020-07-17 | — | — | CN | disclosed |