Benzophenone

Benzophenone

SCHEMBL2843986

CCCCC(OC)(C(=O)c1ccccc1)C(=O)c1ccccc1.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.45
ALDH1A1 P00352 4/20 0.44
PPARA Q07869 1/20 0.43
ELANE P08246 3/20 0.42
CES2 O00748 3/20 0.41
SRC P12931 1/20 0.41
HPGD P15428 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.39
RAB9A P51151 1/20 0.39
NAAA Q02083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15651 0.95 CES1 (0.49) CES1CES2SRCL3MBTL1KMT2A
Methane SCHEMBL16506198 0.94 CES1 (0.47) CES1CES2SRCL3MBTL1KMT2A
Water SCHEMBL28127793 0.94 CES1 (0.47) CES1CES2SRCL3MBTL1KMT2A
SCHEMBL4591841 0.91 CES1 (0.47) CES1CES2SRCLMNANAAA
SCHEMBL8083975 0.89 CES1 (0.47) CES1CES2SRCNAAA
Pyrrole SCHEMBL27588201 0.88 CES1 (0.43) CES1CES2SRCL3MBTL1KMT2A
Dibenzoylmethane SCHEMBL2905077 0.88 KMT2A (0.49) CES1ALDH1A1CES2SRCHPGD
SCHEMBL19031192 0.87 MAPT (0.54) CES1ALDH1A1ELANESRCLMNA
SCHEMBL21239897 0.86 CES1 (0.41) CES1CES2SRCL3MBTL1KMT2A
SCHEMBL19717693 0.85 CES1 (0.40) CES1ALDH1A1CES2SRCL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2252154-B1 METHOD FOR MINIMIZING THE CYTOTOXICITY OF THE EFFECTIVE AGENT IN A COMPOSITION THAT IS ADMINISTERED TO A MAMMAL OR GETS INTO CONTACT WITH A MAMMAL OY GRANULA AB LTD (FI) 2016-01-27 EP disclosed
US-8496974-B2 Method for preparing a composition comprising a compound mixture and a carrier agent OY GRANULA AB LTD (FI) 2013-07-30 US disclosed
US-8414933-B2 Brassocattleya marcella koss orchid extract and use thereof as skin depigmentation agent L V M H RECHERCHE (FR) 2013-04-09 US disclosed
US-8293287-B2 Use of a Brassocattleya marcella Koss orchid extract as an active agent to prevent or delay the appearance of signs of cutaneous aging L V M H RECHERCHE (FR) 2012-10-23 US disclosed
EP-2252154-A2 METHOD FOR MINIMIZING THE CYTOTOXICITY OF THE EFFECTIVE AGENT IN A COMPOSITION THAT IS ADMINISTERED TO A MAMMAL OR GETS INTO CONTACT WITH A MAMMAL Oy Granula AB LTD (FI) 2010-11-24 EP disclosed
US-20100129304-A1 METHOD FOR PREPARING A COMPOSITION COMPRISING A COMPOUND MIXTURE AND A CARRIER AGENT OY GRANULA AB LTD (FI) 2010-05-27 US disclosed
US-20090258093-A1 Use of a brassocattleya marcella koss orchid extract as an active agent to prevent or delay the appearance of signs of cutaneous aging L.V.M.H. RECHERCHE 2009-10-15 US disclosed
US-20090232758-A1 Brassocattleya marcella koss orchid extract and use thereof as skin depigmentation agent L V M H RECHERCHE 2009-09-17 US disclosed
WO-2009101261-A2 METHOD FOR MINIMIZING THE CYTOTOXICITY OF THE EFFECTIVE AGENT IN A COMPOSITION THAT IS ADMINISTERED TO A MAMMAL OR GETS INTO CONTACT WITH A MAMMAL OY GRANULA AB LTD (FI) 2009-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100129304-A1 METHOD FOR PREPARING A COMPOSITION COMPRISING A COMPOUND MIXTURE AND A CARRIER AGENT H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, BAK1, PMAIP1 CES1 1093/4885ALDH1A1 2281/4885PPARA 1431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.