Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.72 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.72 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.72 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.72 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.72 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.72 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22855795 | 0.84 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL21449136 | 0.77 | HDAC6 (0.69) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL12892562 | 0.77 | HDAC6 (0.66) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL30285347 | 0.73 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL1370561 | 0.73 | HDAC6 (0.74) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL28431743 | 0.73 | HDAC6 (0.67) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL22855796 | 0.72 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL3692906 | 0.72 | HDAC6 (0.59) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL30307018 | 0.72 | HDAC6 (0.59) | HDAC6HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL21449098 | 0.71 | HDAC6 (0.77) | HDAC6HDAC1HDAC3HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020921-B | Histone deacetylase HDAC6 inhibitor and preparation method and application thereof | 山东大学 | 2020-08-04 | — | — | CN | disclosed |